YUN Probiotherapy · Belgium

Own the live probiotic category in your market before anyone else can.

YUN pioneered the stabilization of live probiotics in everyday creams and sprays at room temperature. This gives partners a clinically backed, patent-protected platform spanning human skincare, oral and throat care, and animal care.

Two people holding YUN ACN Wash and ACN Repair Cream
  • 78+

    Granted and pending patents

  • 16+

    Peer-reviewed studies

  • 24+ months

    At room temperature

Trusted across human and animal health.

Pharmaceutical and veterinary partners already use YUN's products and technology.

  • Bausch Health

    Pharmaceutical dermatology and skincare.

  • Medinova

    Women's health and dermatology.

  • Animalcare Group

    Veterinary medicines and animal health.

The category gap

The shelves are still built around killing bacteria.

Across common skin and mucosal conditions, antimicrobials are still the default response. They can reduce symptoms, but they do not distinguish between harmful and beneficial microbes, which can leave the underlying microbiome less stable.

The microbiome label

“Microbiome” covers more than living probiotics

A review of 50 cosmetics found 78% of the microbial ingredients were ferments, extracts, filtrates or lysates. Not one product named a living strain.

0 named

Microbial ingredients found

Live strain namedNone

The default response

Antimicrobials take helpful bacteria with them

Antibiotics and antifungals do not target pathogens alone. Dermatology guidelines increasingly recommend limiting their use, because resistance and repeat flare-ups follow.

  • Beneficial
  • Harmful
  • Removed

Before

After

The format gap

Live products stop short of daily formats

Live skincare exists today, but only in specialist formats: oil-based serums, separated systems, tighter storage. The formats people reach for every morning stay out of reach.

  • Oil-based serum
  • Separated system
  • Tighter storage conditions
  • Everyday cream
  • Everyday spray

Everyday creams and sprays remain unclaimed territory for stable live probiotics.

The platform

YUN solved the formulation problem that kept live probiotics out of everyday care.

YUN's patented Probiotherapy platform keeps documented lactobacilli viable in creams and sprays for 24+ months at room temperature, then releases them when the product is applied.

Two YUN scientists in the formulation laboratory
Microencapsulated probiotic powder in a petri dish

We don't kill. We add.

Probiotherapy delivers live probiotics directly to the skin, mouth, throat or ear. This creates a high local dose at the site of imbalance without relying on bacteria to travel through the digestive system.

Once applied, the live probiotics

  • Compete with overgrowing pathogens
  • Support epithelial barrier integrity
  • Reduce inflammatory triggers
YUN ACN Probiotic Repair Cream applied to the skin

Microencapsulation for creams

A protective capsule keeps freeze-dried strains separate from the water inside the cream. Rubbing breaks the capsule, releasing and activating the bacteria on the skin.

YUN FNG Probiotic Repair Spray being sprayed

Water-free technology for sprays

A water-free suspension keeps the probiotic powder viable and evenly distributed. Shaking thins the formula so it sprays cleanly and delivers a consistent dose.

Agar plates with YUN lactobacilli grown into the YUN wordmark

Patented strains and microbiome-safe ingredients

The platform combines L. rhamnosus YUN-S1.0, L. pentosus YUN-V1.0 and L. plantarum YUN-V2.0 with preservatives and surfactants selected to protect the microbiome.

The range

One platform opens three commercial lines.

Start with the range that fits your channel, then expand across the same protected technology.

Human skincare

Live probiotic care across five high-need categories.

Five live-probiotic ranges address atopic-prone skin, acne, intimate care, baby skin and fungus-prone skin, supported by prebiotic cleansers and postbiotic care.

ATO

Eczema, dry and sensitive skin

85% less itch in consumer testing.

ACN

Acne symptoms & impurities

Demonstrated reductions in inflammatory lesions and comedones in clinical studies.

VGN

Women's health and intimate comfort

Reinforces the vaginal microbiome and supports a healthy pH.

BBY

Baby skin care & diaper rash

Helps prevent diaper rash on sensitive baby skin.

FNG

Fungus-prone skin

94% of patients improved in a clinical evaluation.

Oral and throat care

Live probiotics delivered directly to the mouth and throat.

A convenient spray with Vitamin D for immune support, suited to retail, pharmacy and professional recommendation.

TRT

Probiotic Repair Throat/Oral Spray

Delivers live probiotics directly to the mouth and throat, with Vitamin D to support the normal function of the immune system.

Animal care

Live probiotic support for recurrent skin and ear imbalance.

Targeted sprays and ear drops support the microbiome and barrier in dogs and horses, including after antimicrobial treatment.

ATOSkin spray

ATO Repair Spray

Supports the skin microbiome and barrier in dogs.

OTIEar drops

OTI Repair Drops

Helps rebalance the ear microbiome in recurrent imbalance.

HFGSkin spray

HFG Repair Spray

Supports microbiome balance in moisture-driven equine conditions.

The evidence

Scientific evidence and publications.

Peer-reviewed studies and clinical evaluations support products across all three lines.

Human skincare

Cell Reports Medicine

Selective targeting of skin pathobionts and inflammation with topically applied lactobacilli

Double-blind, placebo-controlled

Read the study

Airway and throat

Microbiology Spectrum

Randomized, Double-Blind, Placebo-Controlled Trial of a Throat Spray with Selected Lactobacilli in COVID-19 Outpatients

Randomized, double-blind, placebo-controlled

Read the study

Animal care

Veterinary Dermatology

Clinical Efficacy of Probiotic-Based Ear Drops Containing Lactobacilli in Canine Erythroceruminous Otitis Externa

Open label, multicentre study

Read the study

Human skincare

Airway, nasal and throat care

Women's intimate care

Animal care

Foundational probiotic science

Backed by leading European universities and 78+ granted and pending patents.

The distributor opportunity

Give your portfolio a category competitors cannot easily copy.

Start with the range that fits your strongest channel. Introduce it through the dermatologists, pharmacists, veterinarians or retailers you already work with.

A difference your field team can explain

Probiotherapy gives dermatologists, pharmacists and veterinarians a clear way to discuss microbiome balance. The products fit alongside established care routines to support hydration, barrier recovery and microbial balance.

Granted and pending

78+

Patents

Protected across the platform

YUN holds 78+ granted and pending patents covering strains, formulations, stability and delivery. A competitor would have to solve all four.

Start with one range, then expand

Begin where your channel is strongest, then add adjacent human or animal-health ranges supported by the same science, technology and training.

Cold chain

Room temperature

No cold chain

Room-temperature stability means the products can move through established pharmaceutical and health-retail logistics. Long-term storage still follows the conditions stated in each product dossier.

Go to market

Turn professional trust into market-wide reach.

Professional recommendation gives YUN a clear role in the care routine. Retail makes the products available, and e-commerce extends access across the territory.

Recommended

ACN

Professional recommendation

Retail availability

YUN Probiotherapy

E-commerce reach

Partner fit

A new category needs a partner with market-wide reach.

YUN works with established companies that can build professional recommendation first, expand through retail and extend access through e-commerce across an entire territory.

Who we work with

  • Specialist pharmaceutical companiesAdd YUN to established dermatology, women's-health or consumer-care portfolios backed by medical field teams.
  • National healthcare distributorsLaunch YUN across pharmacies, clinics, professional networks and health retail throughout an entire territory.
  • Consumer-health companies with retail reachTake selected YUN ranges into pharmacy, premium retail and e-commerce, supported by professional recommendation.
  • Veterinary pharmaceutical companiesBring YUN's animal-care range to veterinarians, clinics and specialist retailers through an established veterinary network.

What a strong partner brings

  • Territory-wide sales coverage
  • Established access to healthcare professionals
  • Strong pharmacy, retail and e-commerce reach
  • Compliant storage and distribution
  • Local regulatory and medical expertise
  • Dedicated resources for launch

FAQ

What partners ask before launch.

Classification, registration, logistics and commercial terms vary market by market.

Product and evidence

What makes YUN different from other microbiome products?

Most microbiome products contain ferments, extracts or non-living postbiotics. YUN delivers documented live lactobacilli in patented creams and sprays that remain stable at room temperature.

How do the live probiotics remain stable in everyday creams and sprays?

Microcapsules isolate the strains from water inside creams. In sprays, a water-free suspension keeps the probiotic powder viable and evenly distributed until use.

What storage conditions and shelf life apply to each range?

The products do not require a cold chain and remain stable for 24+ months at room temperature. Controlled storage between 15 and 25°C is recommended.

What clinical evidence supports the different YUN ranges?

YUN is supported by peer-reviewed and clinical studies across human skincare, oral and throat care, women's intimate care and animal care. The full publications are available in the evidence section.

Regulatory and classification

How is each YUN range classified in our market?

Human skincare is generally registered as cosmetics. The oral and throat spray is typically positioned as a food supplement, while animal-care classification depends on local rules and claims.

Which product claims can we use in our market?

YUN provides approved claim territories and supporting evidence. Final wording is adapted to the product classification and local regulatory requirements.

What regulatory dossier and technical documentation does YUN provide?

YUN provides the available technical, safety, stability, strain and clinical documentation. The local partner leads the filing with support from YUN.

How long does registration usually take in a new market?

Timelines depend on the product category, intended claims and local authority. YUN and the partner map the regulatory route before setting the launch schedule.

Partnership and exclusivity

Which partnership models are available?

Partners can launch finished YUN products, co-brand an existing range, co-develop a new product or license selected YUN technology.

Are exclusive territorial rights available?

Yes, for selected ranges and territories. Exclusivity depends on the partner's market coverage, launch plan and agreed commercial commitments.

What commitments are required to secure and maintain exclusivity?

YUN looks for territory-wide sales coverage, professional access, compliant distribution, local regulatory capability and dedicated launch resources.

Launch and support

Which YUN range should we launch first in our market?

Start with the range that fits your strongest professional channel and clearest regulatory route. YUN assesses portfolio fit, market demand and channel access with each partner.

Can we start with one range and expand later?

Yes. YUN recommends entering through the strongest professional channel first, then expanding into adjacent ranges, retail and e-commerce.

What regulatory, medical, training and launch support does YUN provide?

YUN supports product selection, technical and scientific materials, regulatory preparation, product training and launch planning. The local partner leads market execution.

How long does it take to move from agreement to first shipment?

The timeline depends on registration, product availability and whether customization is required. A detailed launch schedule is set once the range, territory and regulatory route are confirmed.

Take the lead on live Probiotherapy.

Bring YUN's finished ranges and patented platform to professionals and consumers across your territory.

  • 78+ granted and pending patents
  • Peer-reviewed clinical evidence

Bacteria aren't the problem. They are the answer.